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Endogenous siRNAs promote proteostasis and longevity in germline-less Caenorhabditis elegans
How lifespan and the rate of aging are set is a key problem in biology. Small RNAs are conserved molecules that impact diverse biological processes through the control of gene expression. However, in contrast to miRNAs, the role of endo-siRNAs in aging remains unexplored. Here, by combining deep seq...
Autores principales: | Cohen-Berkman, Moran, Dudkevich, Reut, Ben-Hamo, Shani, Fishman, Alla, Salzberg, Yehuda, Waldman Ben-Asher, Hiba, Lamm, Ayelet T, Henis-Korenblit, Sivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136021/ https://www.ncbi.nlm.nih.gov/pubmed/32213289 http://dx.doi.org/10.7554/eLife.50896 |
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