A protein quality control pathway at the mitochondrial outer membrane

Maintaining the essential functions of mitochondria requires mechanisms to recognize and remove misfolded proteins. However, quality control (QC) pathways for misfolded mitochondrial proteins remain poorly defined. Here, we establish temperature-sensitive (ts-) peripheral mitochondrial outer membran...

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Detalles Bibliográficos
Autores principales: Metzger, Meredith B, Scales, Jessica L, Dunklebarger, Mitchell F, Loncarek, Jadranka, Weissman, Allan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136024/
https://www.ncbi.nlm.nih.gov/pubmed/32118579
http://dx.doi.org/10.7554/eLife.51065