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A protein quality control pathway at the mitochondrial outer membrane
Maintaining the essential functions of mitochondria requires mechanisms to recognize and remove misfolded proteins. However, quality control (QC) pathways for misfolded mitochondrial proteins remain poorly defined. Here, we establish temperature-sensitive (ts-) peripheral mitochondrial outer membran...
Autores principales: | Metzger, Meredith B, Scales, Jessica L, Dunklebarger, Mitchell F, Loncarek, Jadranka, Weissman, Allan M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136024/ https://www.ncbi.nlm.nih.gov/pubmed/32118579 http://dx.doi.org/10.7554/eLife.51065 |
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