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Evaluation of pharmacokinetic interactions between amoxicillin, clarithromycin, and the potassium-competitive acid blocker YH4808 in healthy subjects

YH4808 is a novel potassium-competitive acid blocker that was developed as a therapeutic agent for gastric acid-related diseases; it may replace proton pump inhibitors, which are widely used in combination with amoxicillin and clarithromycin for Helicobacter pylori eradication. We compared the pharm...

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Detalles Bibliográficos
Autores principales: Lee, Woo Yul, Oh, EunSil, Cui, Mengqi, Kim, Choon Ok, Lim, Yeji, Kim, Hunam, Park, Hyeonsoo, Yoon, Sukyong, Park, Min Soo, Hong, Taegon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136080/
https://www.ncbi.nlm.nih.gov/pubmed/32274381
http://dx.doi.org/10.12793/tcp.2020.28.e5