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Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype

OBJECTIVE: Spinal fusion surgery is a common treatment modality for various pathologic conditions of the spine. The bone morphogenetic protein 2 (BMP2) analogue L51P acts as a general inhibitor of BMP antagonists, whereas it shows a weak affinity for BMP type I receptor. It is suggested that L51P ap...

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Detalles Bibliográficos
Autores principales: May, Rahel D., Frauchiger, Daniela A., Albers, Christoph E., Hofstetter, Willy, Gantenbein, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Spinal Neurosurgery Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136110/
https://www.ncbi.nlm.nih.gov/pubmed/32252157
http://dx.doi.org/10.14245/ns.2040002.001