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Development and In Vitro Evaluation of Stearic Acid Phosphotyrosine Amide as New Excipient for Zeta Potential Changing Self-Emulsifying Drug Delivery Systems
ABSTRACT: PURPOSE: Development of zeta potential changing SEDDS containing newly synthesized derivative stearic acid phosphotyrosine amide. METHODS: Stearoyl chloride was conjugated with phosphotyrosine, which is substrate for the brush border enzyme intestinal alkaline phosphate. The synthesized de...
Autores principales: | Prüfert, Felix, Fischer, Franz, Leichner, Christina, Zaichik, Sergey, Bernkop-Schnürch, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136179/ https://www.ncbi.nlm.nih.gov/pubmed/32253523 http://dx.doi.org/10.1007/s11095-020-02802-2 |
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