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Massive analysis of 64,628 bacterial genomes to decipher water reservoir and origin of mobile colistin resistance genes: is there another role for these enzymes?

Since 2015, new worrying colistin resistance mechanism, mediated by mcr-1 gene has been reported worldwide along with eight newly described variants but their source(s) and reservoir(s) remain largely unexplored. Here, we conducted a massive bioinformatic analysis of bacterial genomes to investigate...

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Detalles Bibliográficos
Autores principales: Khedher, Mariem Ben, Baron, Sophie Alexandra, Riziki, Toilhata, Ruimy, Raymond, Raoult, Didier, Diene, Seydina M., Rolain, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136264/
https://www.ncbi.nlm.nih.gov/pubmed/32249837
http://dx.doi.org/10.1038/s41598-020-63167-5

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