Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles

Hydrogen-deuterium exchange combined with mass spectrometry (HDX-MS) is a widely applied biophysical technique that probes the structure and dynamics of biomolecules without the need for site-directed modifications or bio-orthogonal labels. The mechanistic interpretation of HDX data, however, is oft...

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Detalles Bibliográficos
Autores principales: Bradshaw, Richard T., Marinelli, Fabrizio, Faraldo-Gómez, José D., Forrest, Lucy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136279/
https://www.ncbi.nlm.nih.gov/pubmed/32105651
http://dx.doi.org/10.1016/j.bpj.2020.02.005

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