Study Design of the Phase 3 Sparsentan Versus Irbesartan (DUPLEX) Study in Patients With Focal Segmental Glomerulosclerosis

INTRODUCTION: Focal segmental glomerulosclerosis (FSGS), a histologic lesion in the kidney caused by varied pathophysiological processes, leads to end-stage kidney disease in a large proportion of patients. Sparsentan is a first-in-class orally active compound combining endothelin type A (ET(A)) rec...

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Detalles Bibliográficos
Autores principales: Komers, Radko, Diva, Ulysses, Inrig, Jula K., Loewen, Andrea, Trachtman, Howard, Rote, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136327/
https://www.ncbi.nlm.nih.gov/pubmed/32274453
http://dx.doi.org/10.1016/j.ekir.2019.12.017

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