Molecular Dynamics Ensemble Refinement of Intrinsically Disordered Peptides According to Deconvoluted Spectra from Circular Dichroism

We have developed a computational method of atomistically refining the structural ensemble of intrinsically disordered peptides (IDPs) facilitated by experimental measurements using circular dichroism spectroscopy (CD). A major challenge surrounding this approach stems from the deconvolution of expe...

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Detalles Bibliográficos
Autores principales: Ezerski, Jacob C., Zhang, Pengzhi, Jennings, Nathaniel C., Waxham, M. Neal, Cheung, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136346/
https://www.ncbi.nlm.nih.gov/pubmed/32145192
http://dx.doi.org/10.1016/j.bpj.2020.02.015

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