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Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India
Severe acute malnutrition (SAM) may affect cardiac structure and function. Cardiac changes in sick children with SAM have received little attention in the literature. Children aged 6–60 months with SAM were cases, and age and sex matched children were controls. Cardiac biomarker levels were measured...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136354/ https://www.ncbi.nlm.nih.gov/pubmed/32248924 http://dx.doi.org/10.1016/j.ihj.2020.01.005 |
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author | Jain, Dharmendra Rao, Sunil Kumar Kumar, Dhilip Kumar, Ashok Sihag, Bhupendra Kumar |
author_facet | Jain, Dharmendra Rao, Sunil Kumar Kumar, Dhilip Kumar, Ashok Sihag, Bhupendra Kumar |
author_sort | Jain, Dharmendra |
collection | PubMed |
description | Severe acute malnutrition (SAM) may affect cardiac structure and function. Cardiac changes in sick children with SAM have received little attention in the literature. Children aged 6–60 months with SAM were cases, and age and sex matched children were controls. Cardiac biomarker levels were measured by the quantitative the Enzyme- linked immunosorbent assay (ELISA) method, and echocardiography was used to assess cardiac changes in all children. The study included 76 children in each group. Children with SAM had less left ventricular mass and increased myocardial performance index as compared with controls (p < 0.0001). Cardiac biomarker levels were increased in children with SAM (p < 0.0001). Cardiac changes and biomarker levels were comparable in children with edema and children without edema except creatine kinase-MB (p = 0.01). |
format | Online Article Text |
id | pubmed-7136354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-71363542020-11-01 Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India Jain, Dharmendra Rao, Sunil Kumar Kumar, Dhilip Kumar, Ashok Sihag, Bhupendra Kumar Indian Heart J Research Brief Severe acute malnutrition (SAM) may affect cardiac structure and function. Cardiac changes in sick children with SAM have received little attention in the literature. Children aged 6–60 months with SAM were cases, and age and sex matched children were controls. Cardiac biomarker levels were measured by the quantitative the Enzyme- linked immunosorbent assay (ELISA) method, and echocardiography was used to assess cardiac changes in all children. The study included 76 children in each group. Children with SAM had less left ventricular mass and increased myocardial performance index as compared with controls (p < 0.0001). Cardiac biomarker levels were increased in children with SAM (p < 0.0001). Cardiac changes and biomarker levels were comparable in children with edema and children without edema except creatine kinase-MB (p = 0.01). Elsevier 2019 2020-02-04 /pmc/articles/PMC7136354/ /pubmed/32248924 http://dx.doi.org/10.1016/j.ihj.2020.01.005 Text en © 2020 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Brief Jain, Dharmendra Rao, Sunil Kumar Kumar, Dhilip Kumar, Ashok Sihag, Bhupendra Kumar Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title | Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title_full | Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title_fullStr | Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title_full_unstemmed | Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title_short | Cardiac changes in children hospitalized with severe acute malnutrition: A prospective study at tertiary care center of northern India |
title_sort | cardiac changes in children hospitalized with severe acute malnutrition: a prospective study at tertiary care center of northern india |
topic | Research Brief |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136354/ https://www.ncbi.nlm.nih.gov/pubmed/32248924 http://dx.doi.org/10.1016/j.ihj.2020.01.005 |
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