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CD3ε(+) Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS

Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes encoding proteins involved in the process of VDJ recombination retain partial activity and are classified as hypomorphs. Hypomorphic activity in the products from these genes can...

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Detalles Bibliográficos
Autores principales: Boettcher, Adeline N., Cino-Ozuna, A. Giselle, Solanki, Yash, Wiarda, Jayne E., Putz, Ellie, Owens, Jeana L., Crane, Sara A., Ahrens, Amanda P., Loving, Crystal L., Cunnick, Joan. E., Rowland, Raymond R. R., Charley, Sara E., Dekkers, Jack C. M., Tuggle, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136459/
https://www.ncbi.nlm.nih.gov/pubmed/32296428
http://dx.doi.org/10.3389/fimmu.2020.00510