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CD3ε(+) Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS
Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes encoding proteins involved in the process of VDJ recombination retain partial activity and are classified as hypomorphs. Hypomorphic activity in the products from these genes can...
Autores principales: | Boettcher, Adeline N., Cino-Ozuna, A. Giselle, Solanki, Yash, Wiarda, Jayne E., Putz, Ellie, Owens, Jeana L., Crane, Sara A., Ahrens, Amanda P., Loving, Crystal L., Cunnick, Joan. E., Rowland, Raymond R. R., Charley, Sara E., Dekkers, Jack C. M., Tuggle, Christopher K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136459/ https://www.ncbi.nlm.nih.gov/pubmed/32296428 http://dx.doi.org/10.3389/fimmu.2020.00510 |
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