LncRNA NEAT1 Interacted With DNMT1 to Regulate Malignant Phenotype of Cancer Cell and Cytotoxic T Cell Infiltration via Epigenetic Inhibition of p53, cGAS, and STING in Lung Cancer

PURPOSE: Lung cancer is the main cause of cancer-related mortality worldwide. We report here the biological role of nuclear paraspeckle assembly transcript 1 (NEAT1) in the pathogenesis of lung cancer and the underlying mechanisms. METHODS: Reverse transcription–quantitative polymerase chain reactio...

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Detalles Bibliográficos
Autores principales: Ma, Fang, Lei, Yi-Yu, Ding, Meng-Ge, Luo, Li-Hua, Xie, Yang-Chun, Liu, Xian-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136539/
https://www.ncbi.nlm.nih.gov/pubmed/32296457
http://dx.doi.org/10.3389/fgene.2020.00250

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