Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas

PURPOSE: To review and critique the current state of liquid biopsy in pHGG. MATERIALS AND METHODS: Published literature was reviewed for articles related to liquid biopsy in pediatric glioma and adult glioma with a focus on high-grade gliomas. RESULTS: This review discusses the current state of liqu...

Descripción completa

Detalles Bibliográficos
Autores principales: Dietz, Matthew S., Beach, Catherine Z., Barajas, Ramon, Parappilly, Michael S., Sengupta, Sidharth K., Baird, Lissa C., Ciporen, Jeremy N., Han, Seunggu J., Loret de Mola, Rebecca, Cho, Yoon Jae, Nazemi, Kellie J., McClelland, Shearwood, Wong, Melissa H., Jaboin, Jerry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Critical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136635/
https://www.ncbi.nlm.nih.gov/pubmed/32280814
http://dx.doi.org/10.1016/j.adro.2019.12.008
Descripción
Sumario:PURPOSE: To review and critique the current state of liquid biopsy in pHGG. MATERIALS AND METHODS: Published literature was reviewed for articles related to liquid biopsy in pediatric glioma and adult glioma with a focus on high-grade gliomas. RESULTS: This review discusses the current state of liquid biomarkers of pHGG and their potential applications for liquid biopsy development. CONCLUSIONS: While nascent, the progress toward identifying circulating analytes of pHGG primes the field of neuro-oncoogy for liquid biopsy development.

Ejemplares similares