Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate

The effects of calcium carbonate‐crosslinked sodium alginate on poloxamer hydrogels have been investigated. The mechanical strength, degradability, and thermal stability of hydrogels were characterized. The chemical and physical crosslinking in the composite hydrogels has resulted in an improvement...

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Detalles Bibliográficos
Autores principales: Xu, Ningxia, Xu, Jing, Zheng, Xiaoyan, Hui, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136648/
https://www.ncbi.nlm.nih.gov/pubmed/32269901
http://dx.doi.org/10.1002/open.202000040
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author Xu, Ningxia
Xu, Jing
Zheng, Xiaoyan
Hui, Junfeng
author_facet Xu, Ningxia
Xu, Jing
Zheng, Xiaoyan
Hui, Junfeng
author_sort Xu, Ningxia
collection PubMed
description The effects of calcium carbonate‐crosslinked sodium alginate on poloxamer hydrogels have been investigated. The mechanical strength, degradability, and thermal stability of hydrogels were characterized. The chemical and physical crosslinking in the composite hydrogels has resulted in an improvement of the compressive strength and elasticity of the hydrogels. These mixed hydrogels showed improved mechanical properties, elasticity, and stability as well as environmental responsiveness and injectability.
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spelling pubmed-71366482020-04-08 Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate Xu, Ningxia Xu, Jing Zheng, Xiaoyan Hui, Junfeng ChemistryOpen Full Papers The effects of calcium carbonate‐crosslinked sodium alginate on poloxamer hydrogels have been investigated. The mechanical strength, degradability, and thermal stability of hydrogels were characterized. The chemical and physical crosslinking in the composite hydrogels has resulted in an improvement of the compressive strength and elasticity of the hydrogels. These mixed hydrogels showed improved mechanical properties, elasticity, and stability as well as environmental responsiveness and injectability. John Wiley and Sons Inc. 2020-04-06 /pmc/articles/PMC7136648/ /pubmed/32269901 http://dx.doi.org/10.1002/open.202000040 Text en © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Full Papers
Xu, Ningxia
Xu, Jing
Zheng, Xiaoyan
Hui, Junfeng
Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title_full Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title_fullStr Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title_full_unstemmed Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title_short Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
title_sort preparation of injectable composite hydrogels by blending poloxamers with calcium carbonate‐crosslinked sodium alginate
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136648/
https://www.ncbi.nlm.nih.gov/pubmed/32269901
http://dx.doi.org/10.1002/open.202000040
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AT xujing preparationofinjectablecompositehydrogelsbyblendingpoloxamerswithcalciumcarbonatecrosslinkedsodiumalginate
AT zhengxiaoyan preparationofinjectablecompositehydrogelsbyblendingpoloxamerswithcalciumcarbonatecrosslinkedsodiumalginate
AT huijunfeng preparationofinjectablecompositehydrogelsbyblendingpoloxamerswithcalciumcarbonatecrosslinkedsodiumalginate

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