Cargando…

Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma

Cisplatin is widely used in the treatment of tongue squamous cell carcinoma (TSCC), but its clinical efficacy is limited by drug resistance and toxic side effects. Hence, a novel compound capable of enhancing the anticancer effect of cisplatin while reducing the side effects is urgently needed. We h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xue, Danfeng, Pan, Shu-Ting, Zhou, Xiongming, Ye, Fangfei, Zhou, Qun, Shi, Fanzhe, He, Fei, Yu, Hui, Qiu, Jiaxuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136784/ https://www.ncbi.nlm.nih.gov/pubmed/32308804 http://dx.doi.org/10.1155/2020/5649174

Ejemplares similares

Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin
por: Xin, Yuqi, et al.
Publicado: (2023)

Plumbagin Enhances the Radiosensitivity of Tongue Squamous Cell Carcinoma Cells via Downregulating ATM
por: Pan, Shu-Ting, et al.
Publicado: (2021)

Prognostic significance of an autophagy-related long non-coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma
por: Jiang, Qingkun, et al.
Publicado: (2021)

Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma
por: Pan, Shu-Ting, et al.
Publicado: (2023)

Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells
por: Pan, Shu-Ting, et al.
Publicado: (2015)

Plumbagin induces the apoptosis of human tongue carcinoma cells through the mitochondria-mediated pathway
por: Qiu, Jia-xuan, et al.
Publicado: (2013)

Plumbagin induces G(2)/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells
por: Pan, Shu-Ting, et al.
Publicado: (2015)

Establishment and Identification of Patient-Derived Xenograft Model for Oral Squamous Cell Carcinoma
por: He, Fei, et al.
Publicado: (2022)

Anticancer Effects and Mechanisms of Action of Plumbagin: Review of Research Advances
por: Yin, Zhenhua, et al.
Publicado: (2020)

lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway
por: Jiang, Qingkun, et al.
Publicado: (2021)

Bmi1 Essentially Mediates Podocalyxin-Enhanced Cisplatin Chemoresistance in Oral Tongue Squamous Cell Carcinoma
por: Zhou, Yueying, et al.
Publicado: (2015)

Propylene Glycol Caprylate-Based Nanoemulsion Formulation of Plumbagin: Development and Characterization of Anticancer Activity
por: Chrastina, Adrian, et al.
Publicado: (2022)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation
por: Lee, Ju-Hee, et al.
Publicado: (2012)

Identification of novel potential biomarkers in infantile hemangioma via weighted gene co-expression network analysis
por: Xie, Bin, et al.
Publicado: (2022)

Electrochemical Assessment of Anticancer Compounds on the Human Tongue Squamous Carcinoma Cells
por: Huang, Chun-Chung, et al.
Publicado: (2020)

Plumbagin induces ROS-mediated apoptosis and cell cycle arrest and inhibits EMT in human cervical carcinoma cells
por: Jaiswal, Ankita, et al.
Publicado: (2018)

Anticancer Compound Plumbagin and Its Molecular Targets: A Structural Insight into the Inhibitory Mechanisms Using Computational Approaches
por: Jamal, Mohammad S., et al.
Publicado: (2014)

The Effects of Plumbagin on Pancreatic Cancer: A Mechanistic Network Pharmacology Approach
por: Pan, Qijin, et al.
Publicado: (2019)

Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis
por: Guan, Hong-Hsiang, et al.
Publicado: (2021)

Copper-Plumbagin Complex Produces Potent Anticancer Effects by Depolymerizing Microtubules and Inducing Reactive Oxygen Species and DNA Damage
por: Mukherjee, Sandipan, et al.
Publicado: (2023)

Antimalarial activity of plumbagin in vitro and in animal models
por: Sumsakul, Wiriyaporn, et al.
Publicado: (2014)

Plumbagin analogs-synthesis, characterization, and antitubercular activity
por: Nayak, Nishi, et al.
Publicado: (2014)

Plumbagin Modulates Leukemia Cell Redox Status
por: Gaascht, François, et al.
Publicado: (2014)

Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties
por: Sultanli, Sevinj, et al.
Publicado: (2021)

Inhibition of Intracellular ROS Accumulation by Formononetin Attenuates Cisplatin-Mediated Apoptosis in LLC-PK1 Cells
por: Lee, Haesol, et al.
Publicado: (2018)

Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells
por: Zhou, Zhi-Wei, et al.
Publicado: (2015)

TUG1/miR-133b/CXCR4 axis regulates cisplatin resistance in human tongue squamous cell carcinoma
por: Zhang, Ke, et al.
Publicado: (2020)

Antioxidant Activities of Plumbagin and Its Cu (II) Complex
por: Tan, Mingxiong, et al.
Publicado: (2011)

Plumbagin attenuates Bleomycin-induced lung fibrosis in mice
por: Mehdizadeh, Saber, et al.
Publicado: (2022)

Intracellular claudin‐1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis
por: Yamamoto, Daisuke, et al.
Publicado: (2019)

Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS
por: Li, Heng, et al.
Publicado: (2022)

Transcriptomic dissection of tongue squamous cell carcinoma
por: Ye, Hui, et al.
Publicado: (2008)

Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling
por: Cao, Ying-Ya, et al.
Publicado: (2018)

Utilizing the nanosecond pulse technique to improve antigen intracellular delivery and presentation to treat tongue squamous cell carcinoma
por: Gao, Cen, et al.
Publicado: (2018)

Cytotoxicity Mechanism of Two Naphthoquinones (Menadione and Plumbagin) in Saccharomyces cerevisiae
por: Castro, Frederico Augusto Vieira, et al.
Publicado: (2008)

Pharmacokinetics, toxicity, and cytochrome P450 modulatory activity of plumbagin
por: Sumsakul, Wiriyaporn, et al.
Publicado: (2016)

Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis()
por: Zhang, Si-Ming, et al.
Publicado: (2012)

Transferrin‐bearing liposomes entrapping plumbagin for targeted cancer therapy
por: Sakpakdeejaroen, Intouch, et al.
Publicado: (2019)

Fungal endophytes of Plumbago zeylanica L. enhances plumbagin content
por: Andhale, Namdeo B., et al.
Publicado: (2019)

Selective synergistic anticancer effects of cisplatin and oridonin against human p53-mutant esophageal squamous carcinoma cells
por: Yang, Huiyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1pgqs6o7buf8s4emh22k1vakpe