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A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect

There is a distinct clinical need for new therapies that provide an effective treatment for large bone defect repair. Herein we describe a developmental approach, whereby constructs are primed to mimic certain aspects of bone formation that occur during embryogenesis. Specifically, we directly compa...

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Detalles Bibliográficos
Autores principales:	Freeman, Fiona E., Brennan, Meadhbh Á., Browe, David C., Renaud, Audrey, De Lima, Julien, Kelly, Daniel J., McNamara, Laoise M., Layrolle, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137087/ https://www.ncbi.nlm.nih.gov/pubmed/32296687 http://dx.doi.org/10.3389/fbioe.2020.00230

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