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Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism

BACKGROUND: Polymorphisms in MTHFR gene influence risk and overall survival of patients with brain tumor. Global genomic DNA (gDNA) methylation profile from tumor tissues is replicated in peripheral leukocytes. This study aimed to draw a correlation between rs1801133 MTHFR variants, gDNA methylation...

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Detalles Bibliográficos
Autores principales:	Faria, Giselle M., Soares, Igor D. P., D’Alincourt Salazar, Marcela, Amorim, Marcia R., Pessoa, Bruno L., da Fonseca, Clovis O., Quirico-Santos, Thereza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137265/ https://www.ncbi.nlm.nih.gov/pubmed/32264844 http://dx.doi.org/10.1186/s12885-020-06802-8

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