Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins

BACKGROUND: A critical step in uncovering rules of RNA processing is to study the in vivo regulatory networks of RNA binding proteins (RBPs). Crosslinking and immunoprecipitation (CLIP) methods enable mapping RBP targets transcriptome-wide, but methodological differences present challenges to large-...

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Detalles Bibliográficos
Autores principales: Van Nostrand, Eric L., Pratt, Gabriel A., Yee, Brian A., Wheeler, Emily C., Blue, Steven M., Mueller, Jasmine, Park, Samuel S., Garcia, Keri E., Gelboin-Burkhart, Chelsea, Nguyen, Thai B., Rabano, Ines, Stanton, Rebecca, Sundararaman, Balaji, Wang, Ruth, Fu, Xiang-Dong, Graveley, Brenton R., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137325/
https://www.ncbi.nlm.nih.gov/pubmed/32252787
http://dx.doi.org/10.1186/s13059-020-01982-9

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