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Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis

A hallmark pathology of Alzheimer’s disease (AD) is the formation of amyloid β (Aβ) deposits that exhibit diverse localization and morphologies, ranging from diffuse to cored-neuritic deposits in brain parenchyma, with cerebral vascular deposition in leptomeningeal and parenchymal compartments. Most...

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Detalles Bibliográficos
Autores principales:	Xu, Guilian, Fromholt, Susan E., Chakrabarty, Paramita, Zhu, Fanchao, Liu, Xuefei, Pace, Michael C., Koh, Jin, Golde, Todd E., Levites, Yona, Lewis, Jada, Borchelt, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137436/ https://www.ncbi.nlm.nih.gov/pubmed/32252825 http://dx.doi.org/10.1186/s40478-020-00911-y

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