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Differential CpG DNA methylation in peripheral naïve CD4(+) T-cells in early rheumatoid arthritis patients

BACKGROUND: The genetic risk associated with rheumatoid arthritis (RA) includes genes regulating DNA methylation, one of the hallmarks of epigenetic re-programing, as well as many T-cell genes, with a strong MHC association, pointing to immunogenetic mechanisms as disease triggers leading to chronic...

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Detalles Bibliográficos
Autores principales:	Pitaksalee, R., Burska, A. N., Ajaib, S., Rogers, J., Parmar, R., Mydlova, K., Xie, X., Droop, A., Nijjar, J. S., Chambers, P., Emery, P., Hodgett, R., McInnes, I. B., Ponchel, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137446/ https://www.ncbi.nlm.nih.gov/pubmed/32264938 http://dx.doi.org/10.1186/s13148-020-00837-1

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