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Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer
BACKGROUND: The Vesical Imaging-Reporting and Data System (VI-RADS) was created in 2018, and a 5-point VI-RADS scoring system was proposed to determine whether the muscularis of the bladder has been infiltrated by tumor tissues. PURPOSE: To verify the accuracy of the VI-RADS scoring system in predic...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137481/ https://www.ncbi.nlm.nih.gov/pubmed/32252816 http://dx.doi.org/10.1186/s40644-020-00304-3 |
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author | Wang, Ziyong Shang, Yunyun Luan, Ting Duan, Yi Wang, Jiansong Wang, Haifeng Hao, Jingang |
author_facet | Wang, Ziyong Shang, Yunyun Luan, Ting Duan, Yi Wang, Jiansong Wang, Haifeng Hao, Jingang |
author_sort | Wang, Ziyong |
collection | PubMed |
description | BACKGROUND: The Vesical Imaging-Reporting and Data System (VI-RADS) was created in 2018, and a 5-point VI-RADS scoring system was proposed to determine whether the muscularis of the bladder has been infiltrated by tumor tissues. PURPOSE: To verify the accuracy of the VI-RADS scoring system in predicting muscle-invasive bladder cancer and to explore its value in clinical application. MATERIALS AND METHODS: A total of 220 patients with bladder cancer who underwent multiparameter magnetic resonance imaging from January 2017 to June 2019 were selected. Then, two radiologists with equivalent qualifications gave their diagnoses of bladder tumors on T2-weighted imaging, diffusion-weighted imaging and dynamic contrast enhanced imaging. Meanwhile, the bladder tumor was also scored on the basis of the VI-RADS system; for multifocal tumors, the highest tumor load was selected for scoring. Furthermore, the final pathological results of the patients were unknown during the imaging diagnosis and scoring. Next, the VI-RADS score was compared with the pathological results after surgery, and the ability of the VI-RADS score to assess the degree of muscularis infiltration was finally analyzed. RESULTS: A total of 220 patients were included in our study, including 194 males and 26 females. Among them, the pathological results were 113 cases of muscle-invasive bladder cancer and 107 cases of non-muscle-invasive bladder cancer. The results showed that there was a positive correlation between the pathological results and VI-RADS score (r = 0.821, P < 0.05). The area under the receiver operating characteristic curve of the VI-RADS score was 0.960 (95% CI: 0.937, 0.983). When the VI-RADS score was above 3, the sensitivity, specificity and accuracy of predicting muscle-invasive bladder cancer were 82.3, 95.3 and 88.64%, respectively. CONCLUSION: The VI-RADS scoring system has good diagnostic value in predicting the degree of tumor invasion and can be used to guide clinical decision-making and management. |
format | Online Article Text |
id | pubmed-7137481 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-71374812020-04-11 Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer Wang, Ziyong Shang, Yunyun Luan, Ting Duan, Yi Wang, Jiansong Wang, Haifeng Hao, Jingang Cancer Imaging Research Article BACKGROUND: The Vesical Imaging-Reporting and Data System (VI-RADS) was created in 2018, and a 5-point VI-RADS scoring system was proposed to determine whether the muscularis of the bladder has been infiltrated by tumor tissues. PURPOSE: To verify the accuracy of the VI-RADS scoring system in predicting muscle-invasive bladder cancer and to explore its value in clinical application. MATERIALS AND METHODS: A total of 220 patients with bladder cancer who underwent multiparameter magnetic resonance imaging from January 2017 to June 2019 were selected. Then, two radiologists with equivalent qualifications gave their diagnoses of bladder tumors on T2-weighted imaging, diffusion-weighted imaging and dynamic contrast enhanced imaging. Meanwhile, the bladder tumor was also scored on the basis of the VI-RADS system; for multifocal tumors, the highest tumor load was selected for scoring. Furthermore, the final pathological results of the patients were unknown during the imaging diagnosis and scoring. Next, the VI-RADS score was compared with the pathological results after surgery, and the ability of the VI-RADS score to assess the degree of muscularis infiltration was finally analyzed. RESULTS: A total of 220 patients were included in our study, including 194 males and 26 females. Among them, the pathological results were 113 cases of muscle-invasive bladder cancer and 107 cases of non-muscle-invasive bladder cancer. The results showed that there was a positive correlation between the pathological results and VI-RADS score (r = 0.821, P < 0.05). The area under the receiver operating characteristic curve of the VI-RADS score was 0.960 (95% CI: 0.937, 0.983). When the VI-RADS score was above 3, the sensitivity, specificity and accuracy of predicting muscle-invasive bladder cancer were 82.3, 95.3 and 88.64%, respectively. CONCLUSION: The VI-RADS scoring system has good diagnostic value in predicting the degree of tumor invasion and can be used to guide clinical decision-making and management. BioMed Central 2020-04-06 /pmc/articles/PMC7137481/ /pubmed/32252816 http://dx.doi.org/10.1186/s40644-020-00304-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Wang, Ziyong Shang, Yunyun Luan, Ting Duan, Yi Wang, Jiansong Wang, Haifeng Hao, Jingang Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title | Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title_full | Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title_fullStr | Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title_full_unstemmed | Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title_short | Evaluation of the value of the VI-RADS scoring system in assessing muscle infiltration by bladder cancer |
title_sort | evaluation of the value of the vi-rads scoring system in assessing muscle infiltration by bladder cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137481/ https://www.ncbi.nlm.nih.gov/pubmed/32252816 http://dx.doi.org/10.1186/s40644-020-00304-3 |
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