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Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine
Short linear motifs (SLiMs) located in disordered regions of multidomain proteins are important for the organization of protein–protein interaction networks. By dynamic association with their binding partners, SLiMs enable assembly of multiprotein complexes, pivotal for the regulation of various asp...
Autores principales: | Putyrski, Mateusz, Vakhrusheva, Olesya, Bonn, Florian, Guntur, Suchithra, Vorobyov, Andrew, Brandts, Christian, Dikic, Ivan, Ernst, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137635/ https://www.ncbi.nlm.nih.gov/pubmed/32296703 http://dx.doi.org/10.3389/fcell.2020.00208 |
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