Quantitative Evaluation of the Transcriptional Activity of Steroid Hormone Receptor Mutants and Variants Using a Single Vector With Two Reporters and a Receptor Expression Cassette

Although the rapid development of high-throughput sequencing has led to the identification of a large number of truncated or mutated steroid hormone receptor (SHR) variants, their clinical relevance remains to be defined. A platform for functional analysis of these SHR variants in cells would be ins...

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Detalles Bibliográficos
Autores principales: Ji, Huimin, Li, Ying, Liu, Zhao, Tang, Min, Zou, Lihui, Su, Fei, Zhang, Yaqun, Zhang, Junhua, Li, Hexin, Li, Lin, Ai, Bin, Ma, Jie, Wang, Lunan, Liu, Ming, Xiao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137763/
https://www.ncbi.nlm.nih.gov/pubmed/32296391
http://dx.doi.org/10.3389/fendo.2020.00167

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