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MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison

Background: Cortical deceleration is the main reason for bone loss at peripheral sites. It was suggested that when peripheral bones were assessed for osteoporosis, management and therapy can be administered early. The main aim of this study was to assess the relationships between the central and per...

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Autores principales: Malekzadeh, Malakeh, Asadi, Mojgan, Abbasi-Rad, Shahrokh, Abolghasemi, Jamileh, Hamidi, Zohreh, Talebi, Mahsa, Shiran, Mohammad Bagher, Saligheh Rad, Hamidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137819/
https://www.ncbi.nlm.nih.gov/pubmed/32280662
http://dx.doi.org/10.34171/mjiri.33.156
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author Malekzadeh, Malakeh
Asadi, Mojgan
Abbasi-Rad, Shahrokh
Abolghasemi, Jamileh
Hamidi, Zohreh
Talebi, Mahsa
Shiran, Mohammad Bagher
Saligheh Rad, Hamidreza
author_facet Malekzadeh, Malakeh
Asadi, Mojgan
Abbasi-Rad, Shahrokh
Abolghasemi, Jamileh
Hamidi, Zohreh
Talebi, Mahsa
Shiran, Mohammad Bagher
Saligheh Rad, Hamidreza
author_sort Malekzadeh, Malakeh
collection PubMed
description Background: Cortical deceleration is the main reason for bone loss at peripheral sites. It was suggested that when peripheral bones were assessed for osteoporosis, management and therapy can be administered early. The main aim of this study was to assess the relationships between the central and peripheral measurements at different skeleton bone sites (spine, femur, forearm, tibia, and calcaneus) with available modalities: DXA, QUS, and MDCT-QCT. Methods: The volunteers recruited in this study did not have any history or evidence of metabolic bone disease. Blood test and DXA measurements were used as inclusion criteria to select 40 healthy participants. The selected volunteers underwent 3 imaging modalities: QCT, DXA, and QUS. DXA-based measurements were made on 3 sites, including spine, femur, and forearm. QCT and QUS measurements were done for distal of tibia and calcaneus bones, respectively. The extracted parameters from the 3 modalities were analyzed using a bivariate (Pearson) correlation (r) in statistical software. Results: The results showed moderate to good correlations between spongy bones in central and peripheral sites from all the modalities. However, there was no correlation between MDCT measures and central bone values. According to correlations between different peripheral sits, aBMD of 33% radius and trabecular vBMD in 38% distal tibia showed weak but significant relationship between peripheral bones (r=-0.342, p=0.044). Conclusion: The findings demonstrated how bones in central and peripheral sites were correlated. Multimodality imaging was used in this group of healthy volunteers. Also, it was found that QCT-based MDCT needs more optimization and requires further investigations.
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spelling pubmed-71378192020-04-10 MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison Malekzadeh, Malakeh Asadi, Mojgan Abbasi-Rad, Shahrokh Abolghasemi, Jamileh Hamidi, Zohreh Talebi, Mahsa Shiran, Mohammad Bagher Saligheh Rad, Hamidreza Med J Islam Repub Iran Original Article Background: Cortical deceleration is the main reason for bone loss at peripheral sites. It was suggested that when peripheral bones were assessed for osteoporosis, management and therapy can be administered early. The main aim of this study was to assess the relationships between the central and peripheral measurements at different skeleton bone sites (spine, femur, forearm, tibia, and calcaneus) with available modalities: DXA, QUS, and MDCT-QCT. Methods: The volunteers recruited in this study did not have any history or evidence of metabolic bone disease. Blood test and DXA measurements were used as inclusion criteria to select 40 healthy participants. The selected volunteers underwent 3 imaging modalities: QCT, DXA, and QUS. DXA-based measurements were made on 3 sites, including spine, femur, and forearm. QCT and QUS measurements were done for distal of tibia and calcaneus bones, respectively. The extracted parameters from the 3 modalities were analyzed using a bivariate (Pearson) correlation (r) in statistical software. Results: The results showed moderate to good correlations between spongy bones in central and peripheral sites from all the modalities. However, there was no correlation between MDCT measures and central bone values. According to correlations between different peripheral sits, aBMD of 33% radius and trabecular vBMD in 38% distal tibia showed weak but significant relationship between peripheral bones (r=-0.342, p=0.044). Conclusion: The findings demonstrated how bones in central and peripheral sites were correlated. Multimodality imaging was used in this group of healthy volunteers. Also, it was found that QCT-based MDCT needs more optimization and requires further investigations. Iran University of Medical Sciences 2019-12-28 /pmc/articles/PMC7137819/ /pubmed/32280662 http://dx.doi.org/10.34171/mjiri.33.156 Text en © 2019 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Malekzadeh, Malakeh
Asadi, Mojgan
Abbasi-Rad, Shahrokh
Abolghasemi, Jamileh
Hamidi, Zohreh
Talebi, Mahsa
Shiran, Mohammad Bagher
Saligheh Rad, Hamidreza
MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title_full MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title_fullStr MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title_full_unstemmed MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title_short MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
title_sort mdct-qct, qus, and dxa in healthy adults: an intermodality comparison
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137819/
https://www.ncbi.nlm.nih.gov/pubmed/32280662
http://dx.doi.org/10.34171/mjiri.33.156
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