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D(2)EA: Depict the Epidemic Picture of COVID-19

The outbreak of coronavirus disease 2019 (COVID-19) has aroused a global alert. To release social panic and guide future schedules, this article proposes a novel mathematical model, the Delay Differential Epidemic Analyzer (D(2)EA), to analyze the dynamics of epidemic and forecast its future trends....

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Detalles Bibliográficos
Autores principales: Liu, Chenzhengyi, Zhao, Jingwei, Liu, Guohang, Gao, Yuanning, Gao, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai Jiaotong University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137902/
https://www.ncbi.nlm.nih.gov/pubmed/32288418
http://dx.doi.org/10.1007/s12204-020-2170-7
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author Liu, Chenzhengyi
Zhao, Jingwei
Liu, Guohang
Gao, Yuanning
Gao, Xiaofeng
author_facet Liu, Chenzhengyi
Zhao, Jingwei
Liu, Guohang
Gao, Yuanning
Gao, Xiaofeng
author_sort Liu, Chenzhengyi
collection PubMed
description The outbreak of coronavirus disease 2019 (COVID-19) has aroused a global alert. To release social panic and guide future schedules, this article proposes a novel mathematical model, the Delay Differential Epidemic Analyzer (D(2)EA), to analyze the dynamics of epidemic and forecast its future trends. Based on the traditional Susceptible-Exposed-Infectious-Recovered (SEIR) model, the D(2)EA model innovatively introduces a set of quarantine states and applies both ordinary differential equations and delay differential equations to describe the transition between two states. Potential variations of practical factors are further considered to reveal the true epidemic picture. In the experiment part, we use the D(2)EA model to simulate the epidemic in Hubei Province. Fitting to the collected real data as non-linear optimization, the D(2)EA model forecasts that the accumulated confirmed infected cases in Hubei Province will reach the peak at the end of February and then steady down. We also evaluate the effectiveness of the quarantine measures and schedule the date to reopen Hubei Province.
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spelling pubmed-71379022020-04-07 D(2)EA: Depict the Epidemic Picture of COVID-19 Liu, Chenzhengyi Zhao, Jingwei Liu, Guohang Gao, Yuanning Gao, Xiaofeng J Shanghai Jiaotong Univ Sci Article The outbreak of coronavirus disease 2019 (COVID-19) has aroused a global alert. To release social panic and guide future schedules, this article proposes a novel mathematical model, the Delay Differential Epidemic Analyzer (D(2)EA), to analyze the dynamics of epidemic and forecast its future trends. Based on the traditional Susceptible-Exposed-Infectious-Recovered (SEIR) model, the D(2)EA model innovatively introduces a set of quarantine states and applies both ordinary differential equations and delay differential equations to describe the transition between two states. Potential variations of practical factors are further considered to reveal the true epidemic picture. In the experiment part, we use the D(2)EA model to simulate the epidemic in Hubei Province. Fitting to the collected real data as non-linear optimization, the D(2)EA model forecasts that the accumulated confirmed infected cases in Hubei Province will reach the peak at the end of February and then steady down. We also evaluate the effectiveness of the quarantine measures and schedule the date to reopen Hubei Province. Shanghai Jiaotong University Press 2020-04-07 2020 /pmc/articles/PMC7137902/ /pubmed/32288418 http://dx.doi.org/10.1007/s12204-020-2170-7 Text en © Shanghai Jiao Tong University and Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Liu, Chenzhengyi
Zhao, Jingwei
Liu, Guohang
Gao, Yuanning
Gao, Xiaofeng
D(2)EA: Depict the Epidemic Picture of COVID-19
title D(2)EA: Depict the Epidemic Picture of COVID-19
title_full D(2)EA: Depict the Epidemic Picture of COVID-19
title_fullStr D(2)EA: Depict the Epidemic Picture of COVID-19
title_full_unstemmed D(2)EA: Depict the Epidemic Picture of COVID-19
title_short D(2)EA: Depict the Epidemic Picture of COVID-19
title_sort d(2)ea: depict the epidemic picture of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137902/
https://www.ncbi.nlm.nih.gov/pubmed/32288418
http://dx.doi.org/10.1007/s12204-020-2170-7
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