Evaluation of the silkworm lemon mutant as an invertebrate animal model for human sepiapterin reductase deficiency

Human sepiapterin reductase (SR) deficiency is an inherited disease caused by SPR gene mutations and is a monoamine neurotransmitter disorder. Here, we investigated whether the silkworm lemon mutant could serve as a model of SR deficiency. A point mutation in the BmSPR gene led to a five amino acid...

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Detalles Bibliográficos
Autores principales: Jiang, Guihua, Song, Jiangbo, Hu, Hai, Tong, Xiaoling, Dai, Fangyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Biochemistry, Cellular and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137946/
https://www.ncbi.nlm.nih.gov/pubmed/32269807
http://dx.doi.org/10.1098/rsos.191888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137946/
https://www.ncbi.nlm.nih.gov/pubmed/32269807
http://dx.doi.org/10.1098/rsos.191888

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