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Localized de novo phospholipid synthesis drives autophagosome biogenesis
During (macro)autophagy, cells form transient organelles, termed autophagosomes, to target a broad spectrum of substrates for degradation critical to cellular and organismal health. Driven by rapid membrane assembly, an initially small vesicle (phagophore) elongates into a large cup-shaped structure...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138244/ https://www.ncbi.nlm.nih.gov/pubmed/32013690 http://dx.doi.org/10.1080/15548627.2020.1725379 |