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miR-21/PTEN pathway mediates the cardioprotection of geniposide against oxidized low-density lipoprotein-induced endothelial injury via suppressing oxidative stress and inflammatory response

Oxidized low-density lipoprotein (ox-LDL)-induced vascular endothelial damage, oxidative stress and inflammation play a vital role in the pathophysiology of atherosclerosis. Geniposide is the primary active ingredient from Gardenia jasminoides Ellis associated with anti-oxidative properties and card...

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Detalles Bibliográficos
Autores principales: Zhou, Song, Sun, Yunjing, Zhao, Kai, Gao, Yanzhou, Cui, Jiangman, Qi, Liping, Huang, Lingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138279/
https://www.ncbi.nlm.nih.gov/pubmed/32323738
http://dx.doi.org/10.3892/ijmm.2020.4520