Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification

Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of breast cancers. Here, we investigated the genetic di...

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Detalles Bibliográficos
Autores principales: Van Bockstal, Mieke R., Agahozo, Marie Colombe, van Marion, Ronald, Atmodimedjo, Peggy N., Sleddens, Hein F. B. M., Dinjens, Winand N. M., Visser, Lindy L., Lips, Esther H., Wesseling, Jelle, van Deurzen, Carolien H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138394/
https://www.ncbi.nlm.nih.gov/pubmed/32058674
http://dx.doi.org/10.1002/1878-0261.12650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138394/
https://www.ncbi.nlm.nih.gov/pubmed/32058674
http://dx.doi.org/10.1002/1878-0261.12650

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