NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma

NEK2 is associated with drug resistance in multiple cancers. Our previous studies indicated that high NEK2 confers inferior survival in multiple myeloma (MM); thus, a better understanding of the mechanisms by which NEK2 induces drug resistance in MM is required. In this study, we discovered that NEK...

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Detalles Bibliográficos
Autores principales: Xia, Jiliang, He, Yanjuan, Meng, Bin, Chen, Shilian, Zhang, Jingyu, Wu, Xuan, Zhu, Yinghong, Shen, Yi, Feng, Xiangling, Guan, Yongjun, Kuang, Chunmei, Guo, Jiaojiao, Lei, Qian, Wu, Yangbowen, An, Gang, Li, Guancheng, Qiu, Lugui, Zhan, Fenghuang, Zhou, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138399/
https://www.ncbi.nlm.nih.gov/pubmed/31955515
http://dx.doi.org/10.1002/1878-0261.12641

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