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Nrf2 deficiency aggravates PM(2.5)-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder

PM(2.5) is a well-known air pollutant threatening public health, and long-term exposure to PM(2.5) increases the risk of cardiovascular diseases. Nrf2 plays a pivotal role in the amelioration of PM(2.5)-induced lung injury. However, if Nrf2 is involved in PM(2.5)-induced heart injury, and the underl...

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Detalles Bibliográficos
Autores principales: Ge, Chenxu, Hu, Linfeng, Lou, Deshuai, Li, Qiang, Feng, Jing, Wu, Yekuan, Tan, Jun, Xu, Minxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138545/
https://www.ncbi.nlm.nih.gov/pubmed/32182211
http://dx.doi.org/10.18632/aging.102906