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Nrf2 deficiency aggravates PM(2.5)-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder
PM(2.5) is a well-known air pollutant threatening public health, and long-term exposure to PM(2.5) increases the risk of cardiovascular diseases. Nrf2 plays a pivotal role in the amelioration of PM(2.5)-induced lung injury. However, if Nrf2 is involved in PM(2.5)-induced heart injury, and the underl...
Autores principales: | Ge, Chenxu, Hu, Linfeng, Lou, Deshuai, Li, Qiang, Feng, Jing, Wu, Yekuan, Tan, Jun, Xu, Minxuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138545/ https://www.ncbi.nlm.nih.gov/pubmed/32182211 http://dx.doi.org/10.18632/aging.102906 |
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