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Time-dependent interactions of blood platelets and cancer cells, accompanied by extramedullary hematopoiesis, lead to increased platelet activation and reactivity in a mouse orthotopic model of breast cancer – implications for pulmonary and liver metastasis
Aging has become a significant risk factor for several diseases, including breast cancer. Platelet activation and platelet-cancer cell aggregate fractions were found to increase with tumor progression in a mouse model of breast cancer. At advanced stages of tumor development, platelets from mice wit...
Autores principales: | Kassassir, Hassan, Karolczak, Kamil, Siewiera, Karolina M., Wojkowska, Dagmara W., Braun, Marcin, Watala, Cezary W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138580/ https://www.ncbi.nlm.nih.gov/pubmed/32191918 http://dx.doi.org/10.18632/aging.102933 |
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