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Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters

Detoxication, or ‘drug‐metabolizing’, enzymes and drug transporters exhibit remarkable substrate promiscuity and catalytic promiscuity. In contrast to substrate‐specific enzymes that participate in defined metabolic pathways, individual detoxication enzymes must cope with substrates of vast structur...

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Detalles Bibliográficos
Autor principal:	Atkins, William M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138722/ https://www.ncbi.nlm.nih.gov/pubmed/31663687 http://dx.doi.org/10.1111/febs.15116

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