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Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites

The Glutathione S-transferases (GSTs) protects cellular DNA against oxidative damage. The role of GSTP1 polymorphism (A313G; Ile105Val) as a susceptibility factor in oral cancer was evaluated in a hospital-based case-control study in North-East India, because the habit of chewing raw areca-nut (RAN)...

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Detalles Bibliográficos
Autores principales:	Yadav, Pallavi, Banerjee, Atanu, Boruah, Nabamita, Singh, Chongtham Sovachandra, Chatterjee, Puja, Mukherjee, Souvik, Dakhar, Hughbert, Nongrum, Henry B., Bhattacharjee, Atanu, Chatterjee, Anupam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138809/ https://www.ncbi.nlm.nih.gov/pubmed/32265484 http://dx.doi.org/10.1038/s41598-020-63034-3

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