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Autophagy inhibition potentiates the anti-EMT effects of alteronol through TGF-β/Smad3 signaling in melanoma cells

Accumulating evidence demonstrated that alteronol, a novel compound that has a similar structure with paclitaxel, exerts anticancer effects against diversified tumors. However, whether alteronol induces autophagy and the relationship between its anticancer effects and autophagy in melanoma remains e...

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Detalles Bibliográficos
Autores principales: Bao, Yong, Ding, Zhi, Zhao, Peng, Li, Jun, Chen, Ping, Zheng, Jie, Qian, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138813/
https://www.ncbi.nlm.nih.gov/pubmed/32265437
http://dx.doi.org/10.1038/s41419-020-2419-y