Cargando…
Autophagy inhibition potentiates the anti-EMT effects of alteronol through TGF-β/Smad3 signaling in melanoma cells
Accumulating evidence demonstrated that alteronol, a novel compound that has a similar structure with paclitaxel, exerts anticancer effects against diversified tumors. However, whether alteronol induces autophagy and the relationship between its anticancer effects and autophagy in melanoma remains e...
Autores principales: | Bao, Yong, Ding, Zhi, Zhao, Peng, Li, Jun, Chen, Ping, Zheng, Jie, Qian, Zhongming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138813/ https://www.ncbi.nlm.nih.gov/pubmed/32265437 http://dx.doi.org/10.1038/s41419-020-2419-y |
Ejemplares similares
-
Alternol/Alteronol: Potent Anti-cancer Compounds With Multiple Mechanistic Actions
por: Liu, Wang, et al.
Publicado: (2020) -
Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer
por: Ren, Boxue, et al.
Publicado: (2019) -
Jieduquyuzishen Prescription Attenuates Renal Fibrosis in MRL/lpr Mice via Inhibiting EMT and TGF-β1/Smad2/3 Pathway
por: Wu, Shan, et al.
Publicado: (2022) -
TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment
por: Dash, Subhra, et al.
Publicado: (2018) -
Anti-tumor Drug THZ1 Suppresses TGFβ2-mediated EMT in Lens Epithelial Cells via Notch and TGFβ/Smad Signaling Pathway
por: Ning, Jie, et al.
Publicado: (2019)