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Selection or drift: The population biology underlying transposon insertion sequencing experiments

Transposon insertion sequencing methods such as Tn-seq revolutionized microbiology by allowing the identification of genomic loci that are critical for viability in a specific environment on a genome-wide scale. While powerful, transposon insertion sequencing suffers from limited reproducibility whe...

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Detalles Bibliográficos
Autores principales: Mahmutovic, Anel, Abel zur Wiesch, Pia, Abel, Sören
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138912/
https://www.ncbi.nlm.nih.gov/pubmed/32280434
http://dx.doi.org/10.1016/j.csbj.2020.03.021

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