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Selection or drift: The population biology underlying transposon insertion sequencing experiments
Transposon insertion sequencing methods such as Tn-seq revolutionized microbiology by allowing the identification of genomic loci that are critical for viability in a specific environment on a genome-wide scale. While powerful, transposon insertion sequencing suffers from limited reproducibility whe...
Autores principales: | Mahmutovic, Anel, Abel zur Wiesch, Pia, Abel, Sören |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138912/ https://www.ncbi.nlm.nih.gov/pubmed/32280434 http://dx.doi.org/10.1016/j.csbj.2020.03.021 |
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