Copy‐number analysis of Y‐linked loci in young men with non‐obstructive azoospermia: Implications for the rarity of early onset mosaic loss of chromosome Y

PURPOSE: Mosaic loss of chromosome Y (mLOY) is a common feature in elderly men. If mLOY can also occur in young men, it may lead to spermatogenic failure due to loss of spermatogenic genes. Indeed, previous studies detected the 45,X/46,XY karyotype in a few young men with spermatogenic failure. The...

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Detalles Bibliográficos
Autores principales: Suzuki, Erina, Kobori, Yoshitomo, Katsumi, Momori, Ushijima, Kikumi, Uchiyama, Toru, Okada, Hiroshi, Miyado, Mami, Fukami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138941/
https://www.ncbi.nlm.nih.gov/pubmed/32273824
http://dx.doi.org/10.1002/rmb2.12321

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