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Inhibition of the endoplasmic reticulum (ER) stress-associated IRE-1/XBP-1 pathway alleviates acute lung injury via modulation of macrophage activation

BACKGROUND: Both endoplasmic reticulum (ER) stress and macrophage diversity contribute to inflammatory processes in lung injury. However, the interaction between ER stress and macrophage M1/M2 imbalance in lung inflammation remains unclear. The present study, thus, aimed to evaluate the role of ER s...

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Detalles Bibliográficos
Autores principales: Zhao, Yanfeng, Jiang, Yan, Chen, Linsong, Zheng, Xinlin, Zhu, Junjie, Song, Xiao, Shi, Jinghan, Li, Yuping, He, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139036/
https://www.ncbi.nlm.nih.gov/pubmed/32274095
http://dx.doi.org/10.21037/jtd.2020.01.45