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Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer
BACKGROUND: Pembrolizumab is recommended as first-line therapy for patients with advanced non-small cell lung cancer (NSCLC) and a Programmed cell death ligand-1 (PD-L1) tumor proportion score (TPS) of ≥50% without driver mutations. However, the safety and efficacy were not investigated among patien...
Autores principales: | Masuda, Takeshi, Fujitaka, Kazunori, Ishikawa, Nobuhisa, Nakano, Kikuo, Yamasaki, Masahiro, Kitaguchi, Souichi, Masuda, Ken, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Kawase, Shigeo, Miyamoto, Shintaro, Nakashima, Taku, Iwamoto, Hiroshi, Shiota, Naoki, Senoo, Tadashi, Awaya, Yoshikazu, Kondo, Tomohiro, Yoshida, Takashi, Hamada, Hironobu, Murakami, Isao, Hattori, Noboru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139059/ https://www.ncbi.nlm.nih.gov/pubmed/32274176 http://dx.doi.org/10.21037/jtd.2019.12.46 |
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