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Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis

BACKGROUND: The operative treatment of Achilles tendon ruptures has been associated with lower rerupture rates and better function but also a risk of surgery-related complications compared with nonoperative treatment, which may provide improved outcomes with accelerated rehabilitation protocols. How...

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Autores principales: Su, Alvin W., Bogunovic, Ljiljana, Johnson, Jeffrey, Klein, Sandra, Matava, Matthew J., McCormick, Jeremy, Smith, Matthew V., Wright, Rick W., Brophy, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139191/
https://www.ncbi.nlm.nih.gov/pubmed/32284940
http://dx.doi.org/10.1177/2325967120909918
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author Su, Alvin W.
Bogunovic, Ljiljana
Johnson, Jeffrey
Klein, Sandra
Matava, Matthew J.
McCormick, Jeremy
Smith, Matthew V.
Wright, Rick W.
Brophy, Robert H.
author_facet Su, Alvin W.
Bogunovic, Ljiljana
Johnson, Jeffrey
Klein, Sandra
Matava, Matthew J.
McCormick, Jeremy
Smith, Matthew V.
Wright, Rick W.
Brophy, Robert H.
author_sort Su, Alvin W.
collection PubMed
description BACKGROUND: The operative treatment of Achilles tendon ruptures has been associated with lower rerupture rates and better function but also a risk of surgery-related complications compared with nonoperative treatment, which may provide improved outcomes with accelerated rehabilitation protocols. However, economic decision analyses integrating the updated costs of both treatment options are limited in the literature. PURPOSE: To compare the cost-effectiveness of operative and nonoperative treatment of acute Achilles tendon tears. STUDY DESIGN: Economic and decision analysis; Level of evidence, 2. METHODS: An economic decision model was built to assess the cost-utility ratio (CUR) of open primary repair versus nonoperative treatment for acute Achilles tendon ruptures, based on direct costs from the practices of sports medicine and foot and ankle surgeons at a single tertiary academic center, with published outcome probabilities and patient utility data. Multiway sensitivity analyses were performed to reflect the range of data. RESULTS: Nonoperative treatment was more cost-effective in the average scenario (nonoperative CUR, US$520; operative CUR, US$1995), but crossover occurred during the sensitivity analysis (nonoperative CUR range, US$224-US$2079; operative CUR range, US$789-US$8380). Operative treatment cost an extra average marginal CUR of US$1475 compared with nonoperative treatment, assuming uneventful healing in both treatment arms. The sensitivity analysis demonstrated a decreased marginal CUR of operative treatment when the outcome utility was maximized, and rerupture rates were minimized compared with nonoperative treatment. CONCLUSION: Nonoperative treatment was more cost-effective in average scenarios. Crossover indicated that open primary repair would be favorable for maximized outcome utility, such as that for young athletes or heavy laborers. The treatment decision for acute Achilles tendon ruptures should be individualized. These pilot results provide inferences for further longitudinal analyses incorporating future clinical evidence.
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spelling pubmed-71391912020-04-13 Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis Su, Alvin W. Bogunovic, Ljiljana Johnson, Jeffrey Klein, Sandra Matava, Matthew J. McCormick, Jeremy Smith, Matthew V. Wright, Rick W. Brophy, Robert H. Orthop J Sports Med Article BACKGROUND: The operative treatment of Achilles tendon ruptures has been associated with lower rerupture rates and better function but also a risk of surgery-related complications compared with nonoperative treatment, which may provide improved outcomes with accelerated rehabilitation protocols. However, economic decision analyses integrating the updated costs of both treatment options are limited in the literature. PURPOSE: To compare the cost-effectiveness of operative and nonoperative treatment of acute Achilles tendon tears. STUDY DESIGN: Economic and decision analysis; Level of evidence, 2. METHODS: An economic decision model was built to assess the cost-utility ratio (CUR) of open primary repair versus nonoperative treatment for acute Achilles tendon ruptures, based on direct costs from the practices of sports medicine and foot and ankle surgeons at a single tertiary academic center, with published outcome probabilities and patient utility data. Multiway sensitivity analyses were performed to reflect the range of data. RESULTS: Nonoperative treatment was more cost-effective in the average scenario (nonoperative CUR, US$520; operative CUR, US$1995), but crossover occurred during the sensitivity analysis (nonoperative CUR range, US$224-US$2079; operative CUR range, US$789-US$8380). Operative treatment cost an extra average marginal CUR of US$1475 compared with nonoperative treatment, assuming uneventful healing in both treatment arms. The sensitivity analysis demonstrated a decreased marginal CUR of operative treatment when the outcome utility was maximized, and rerupture rates were minimized compared with nonoperative treatment. CONCLUSION: Nonoperative treatment was more cost-effective in average scenarios. Crossover indicated that open primary repair would be favorable for maximized outcome utility, such as that for young athletes or heavy laborers. The treatment decision for acute Achilles tendon ruptures should be individualized. These pilot results provide inferences for further longitudinal analyses incorporating future clinical evidence. SAGE Publications 2020-03-31 /pmc/articles/PMC7139191/ /pubmed/32284940 http://dx.doi.org/10.1177/2325967120909918 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Su, Alvin W.
Bogunovic, Ljiljana
Johnson, Jeffrey
Klein, Sandra
Matava, Matthew J.
McCormick, Jeremy
Smith, Matthew V.
Wright, Rick W.
Brophy, Robert H.
Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title_full Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title_fullStr Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title_full_unstemmed Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title_short Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis
title_sort operative versus nonoperative treatment of acute achilles tendon ruptures: a pilot economic decision analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139191/
https://www.ncbi.nlm.nih.gov/pubmed/32284940
http://dx.doi.org/10.1177/2325967120909918
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