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Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations

Escherichia coli lipoprotein precursors at the inner membrane undergo three maturation stages before transport by the Lol system to the outer membrane. Here, we develop a pipeline to simulate the membrane association of bacterial lipoproteins in their four maturation states. This has enabled us to m...

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Detalles Bibliográficos
Autores principales: Rao, Shanlin, Bates, George T., Matthews, Callum R., Newport, Thomas D., Vickery, Owen N., Stansfeld, Phillip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139219/
https://www.ncbi.nlm.nih.gov/pubmed/32053772
http://dx.doi.org/10.1016/j.str.2020.01.012