Pic-Producing Escherichia coli Induces High Production of Proinflammatory Mediators by the Host Leading to Death by Sepsis

Escherichia coli is an important pathogen responsible for a variety of diseases. We have recently shown that Pic, a serine protease secreted by E. coli, mediates immune evasion by the direct cleavage of complement molecules. The aim of this study was to investigate the action of a Pic-producing bact...

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Detalles Bibliográficos
Autores principales: Dutra, Itaynara L., Araújo, Lorena G., Assunção, Raissa G., Lima, Yago A., Nascimento, Johnny R., Vale, André A. M., Alves, Patrícia C. S., Trovão, Liana O., Santos, Ana Carolina M., Silva, Rosa M., Silva, Lucilene A., Maciel, Márcia C. G., de Sousa, Eduardo M., Elias, Waldir P., Nascimento, Flávia R. F., Abreu, Afonso G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139334/
https://www.ncbi.nlm.nih.gov/pubmed/32197297
http://dx.doi.org/10.3390/ijms21062068

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