Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer

Deregulated cellular apoptosis is a hallmark of cancer and chemotherapy resistance. The B-cell lymphoma 2 (BCL-2) protein family members are sentinel molecules that regulate the mitochondrial apoptosis machinery and arbitrate cell fate through a delicate balance between pro- and anti-apoptotic facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Ngoi, Natalie Yan Li, Choong, Clarice, Lee, Joanne, Bellot, Gregory, Wong, Andrea LA, Goh, Boon Cher, Pervaiz, Shazib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139457/
https://www.ncbi.nlm.nih.gov/pubmed/32131385
http://dx.doi.org/10.3390/cancers12030574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139457/
https://www.ncbi.nlm.nih.gov/pubmed/32131385
http://dx.doi.org/10.3390/cancers12030574

Ejemplares similares