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Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer

Deregulated cellular apoptosis is a hallmark of cancer and chemotherapy resistance. The B-cell lymphoma 2 (BCL-2) protein family members are sentinel molecules that regulate the mitochondrial apoptosis machinery and arbitrate cell fate through a delicate balance between pro- and anti-apoptotic facto...

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Detalles Bibliográficos
Autores principales:	Ngoi, Natalie Yan Li, Choong, Clarice, Lee, Joanne, Bellot, Gregory, Wong, Andrea LA, Goh, Boon Cher, Pervaiz, Shazib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139457/ https://www.ncbi.nlm.nih.gov/pubmed/32131385 http://dx.doi.org/10.3390/cancers12030574

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