Cargando…

Insights into Interactions of Flavanones with Target Human Respiratory Syncytial Virus M(2-1) Protein from STD-NMR, Fluorescence Spectroscopy, and Computational Simulations

The human Respiratory Syncytial Virus (hRSV) is the most frequent agent of respiratory infections in infants and children with no currently approved vaccine. The M(2-1) protein is an important transcriptional antitermination factor and a potential target for viral replication inhibitor development....

Descripción completa

Detalles Bibliográficos
Autores principales:	Piva, Hêmily M. R., Sá, Jéssica M., Miranda, Artemiza S., Tasic, Ljubica, Fossey, Marcelo A., Souza, Fátima P., Caruso, Ícaro P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139479/ https://www.ncbi.nlm.nih.gov/pubmed/32213871 http://dx.doi.org/10.3390/ijms21062241

Ejemplares similares

Biophysical and flavonoid-binding studies of the G protein ectodomain of group A human respiratory syncytial virus
por: Machado, Vitor Brassolatti, et al.
Publicado: (2019)

Differential Epitope Mapping by STD NMR Spectroscopy To Reveal the Nature of Protein–Ligand Contacts
por: Monaco, Serena, et al.
Publicado: (2017)

Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies
por: Zafar, Humaira, et al.
Publicado: (2021)

Applications of fluorescence spectroscopy in protein conformational changes and intermolecular contacts
por: dos Santos Rodrigues, Fábio Henrique, et al.
Publicado: (2023)

Deriving Ligand Orientation in Weak Protein–Ligand Complexes by DEEP‐STD NMR Spectroscopy in the Absence of Protein Chemical‐Shift Assignment
por: Nepravishta, Ridvan, et al.
Publicado: (2018)

A STD-NMR Study of the Interaction of the Anabaena Ferredoxin-NADP(+) Reductase with the Coenzyme
por: Antonini, Lara V., et al.
Publicado: (2014)

Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide
por: Nepravishta, Ridvan, et al.
Publicado: (2021)

Insights into the Interaction Mechanism of DTP3 with MKK7 by Using STD-NMR and Computational Approaches
por: Sandomenico, Annamaria, et al.
Publicado: (2020)

Imaging Saturation Transfer Difference (STD) NMR: Affinity and Specificity of Protein–Ligand Interactions from a Single NMR Sample
por: Monaco, Serena, et al.
Publicado: (2023)

Regulation of bistability in the std fimbrial operon of Salmonella enterica by DNA adenine methylation and transcription factors HdfR, StdE and StdF
por: García-Pastor, Lucía, et al.
Publicado: (2019)

A combined fragment-based virtual screening and STD-NMR approach for the identification of E-cadherin ligands
por: Vasile, Francesca, et al.
Publicado: (2022)

PG quiz: STD and pregnancy!
por: Baxi, Reema Rajesh, et al.
Publicado: (2017)

Synthesis and Evaluation of Flavanones as Anticancer Agents
por: Murti, Y., et al.
Publicado: (2014)

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor
por: Igonet, Sébastien, et al.
Publicado: (2018)

Molecular Recognition Patterns between Vitamin B12 and Proteins Explored through STD-NMR and In Silico Studies
por: Ghosh, Ruchira, et al.
Publicado: (2023)

Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket
por: Monaco, Serena, et al.
Publicado: (2022)

STD Awareness Month — April 2013
Publicado: (2013)

STD Awareness Month — April 2014
Publicado: (2014)

Repurposing of US-FDA approved drugs against SARS-CoV-2 main protease (M(pro)) by using STD-NMR spectroscopy, in silico studies and antiviral assays
por: Khan, Abdul Mateen, et al.
Publicado: (2023)

Insights into the Chemical Biology of Childhood Embryonal Solid Tumors by NMR-Based Metabolomics
por: Quintero Escobar, Melissa, et al.
Publicado: (2019)

Trypanocidal Activity of Flavanone Derivatives
por: Maciel Diogo, Gabriela, et al.
Publicado: (2020)

Diffusion in Model Networks as Studied by NMR and Fluorescence Correlation Spectroscopy
por: Modesti, Giorgio, et al.
Publicado: (2009)

Improving STD testing behavior among high-risk young adults by offering STD testing at a vocational school
por: Spauwen, Laura WL, et al.
Publicado: (2011)

STD patients’ preferences for HIV prevention strategies
por: Castro, Jose G, et al.
Publicado: (2014)

Synthesis Chalones and Their Isomerization into Flavanones and Azaflavanones
por: Rocha, Djenisa H. A., et al.
Publicado: (2019)

Sulfated flavanones and dihydroflavonols from willow
por: Noleto-Dias, Clarice, et al.
Publicado: (2020)

Crystal structures of three newly synthesized flavanone hydrazones
por: Yennawar, Hemant P., et al.
Publicado: (2023)

High-Resolution Magic-Angle Spinning NMR Spectroscopy for Evaluation of Cell Shielding by Virucidal Composites Based on Biogenic Silver Nanoparticles, Flexible Cellulose Nanofibers and Graphene Oxide
por: Stanisic, Danijela, et al.
Publicado: (2022)

HIV/STD pattern and its associated risk factors among male STD clinic attendees in China: a foci for HIV intervention
por: Wang, Qian-Qiu, et al.
Publicado: (2011)

Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach
por: Vasile, Francesca, et al.
Publicado: (2018)

Binding modes of environmental endocrine disruptors to human serum albumin: insights from STD-NMR, ITC, spectroscopic and molecular docking studies
por: Yang, Hongqin, et al.
Publicado: (2017)

Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies
por: Ullah, Asmat, et al.
Publicado: (2022)

A portfolio of AIDS/STD behavioral interventions and research

MIL-STD-1553-B and the Next Generation Conference
Publicado: (1989)

Biological Properties and Absolute Configuration of Flavanones From Calceolaria thyrsiflora Graham
por: Valdés, Ernesto, et al.
Publicado: (2020)

Domain-specific interactions between MLN8237 and human serum albumin estimated by STD and WaterLOGSY NMR, ITC, spectroscopic, and docking techniques
por: Yang, Hongqin, et al.
Publicado: (2017)

Development of Non-Natural Flavanones as Antimicrobial Agents
por: Fowler, Zachary L., et al.
Publicado: (2011)

Naringenin: an analgesic and anti-inflammatory citrus flavanone
por: Manchope, Marília F., et al.
Publicado: (2016)

Screening Anti-Inflammatory Effects of Flavanones Solutions
por: Bustos-Salgado, Paola, et al.
Publicado: (2021)

Molecular Characterisation of Flavanone O-methylation in Eucalyptus
por: Somaletha Chandran, Krishna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_aagjm0nb8l3rds9t144cddjabo