Targeted Krüppel-Like Factor 4 Gene Knock-Out in Retinal Ganglion Cells Improves Visual Function in Multiple Sclerosis Mouse Model

Axonal demyelination injury and neuronal degeneration are the primary causes of visual disability in multiple sclerosis (MS)-linked optic neuritis patients. Immunomodulatory therapies targeting inflammation have failed to avert the disease progression and no therapies exist to prevent the neuronal d...

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Detalles Bibliográficos
Autores principales: Talla, Venu, Koilkonda, Rajeshwari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139550/
https://www.ncbi.nlm.nih.gov/pubmed/32165410
http://dx.doi.org/10.1523/ENEURO.0320-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139550/
https://www.ncbi.nlm.nih.gov/pubmed/32165410
http://dx.doi.org/10.1523/ENEURO.0320-19.2020

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